Histopathological Evaluation of Di-Ethyl Phthalate Induced Hepatotoxicity on Rat
نویسندگان
چکیده
منابع مشابه
Hepatotoxic evaluation in di-ethyl phthalate (DEP)-exposed goldfish
The extensive use of di-ethyl phthalate (DEP) as a plasticizer in plastic products, is a major threat to organisms as it leaches out easily from the plastic matrix into the environment. In this study, we evaluated the hepatotoxicity in goldfish (Carassius auratus) upon treatment with DEP. The 96 hr acute DEP LC50 value was determined as > 4 mg/L, using probit analysis. Three sub-lethal concentr...
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Phospholipase D (PLD) is an enzyme that catalyzes the hydrolysis of phosphatidyl choline (PC) to generate phosphatidic acid (PA) and choline. PLD is believed to play an important role in cell proliferation, survival signaling, cell transformation, and tumor progression. However, it remains to be determined whether enhanced expression of PLD in liver is sufficient to induce hepatotoxicity. The a...
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ژورنال
عنوان ژورنال: MOJ Toxicology
سال: 2015
ISSN: 2379-6294
DOI: 10.15406/mojt.2015.02.00019